
Entrepreneur; Co-founder, Cost Plus Drugs
Post-partisan dealmaker's creed: the real enemy isn't red or blue, it's the middleman — and he'll stand next to any president, even the one he called lousy, to prove it.
The Shark Tank billionaire who barnstormed for Harris in 2024 and called Trump 'a lousy president' spent 2025 flogging Democrats for content-free 'Trump sucks' messaging — then walked into Trump's White House in May 2026 to plug Cost Plus Drugs into TrumpRx.gov, enraging his liberal backers. He has ruled out 2028 unless Trump seeks a third term ('a true threat'), still feuds with Musk over DEI and X, and insists drug-price transparency beats party loyalty every time.
Endorsed and campaigned for Harris in 2024 and defends DEI against Musk, but self-identifies as an independent, attacks Democratic messaging, and now partners with the Trump administration on drug pricing. Editorial estimate: a center-left independent who resists the label.
Stances are editorial interpretations, always shown with the statements and actions they rest on.
Since 2022 he has sold generics at cost plus a flat 15% and crusaded against pharmacy benefit managers as the hidden tax on patients. He frames the 2026 TrumpRx partnership as proof he will work with any administration to cut what Americans pay.
Launched the Mark Cuban Cost Plus Drug Company online pharmacy, selling roughly 100 generic medications at manufacturer cost plus a flat 15% markup and pledging 'radically transparent' pricing — e.g. the cancer generic imatinib at $47.40 versus a retail price above $9,657.
Launch of his flagship post-Mavericks venture, built around the mission that every American should have access to safe, affordable medicines at the lowest possible price.
This is a special announcement, this is a special partnership — 559 of those drugs are ours, so we're really excited to be part of this.
Speaking beside President Trump at a White House event announcing that TrumpRx.gov would list 600+ generic drugs through partnerships with Cost Plus Drugs, Amazon Pharmacy and GoodRx.
The sight of Harris's 2024 surrogate promoting a Trump-branded platform at the White House set off days of outrage from his liberal backers and wall-to-wall cable and social coverage.
Get the party to drop pure anti-Trump messaging and campaign on concretely lowering Americans' cost of living, starting with healthcare.
Declared: 2025-07-14Source ↗
Grow Cost Plus Drugs — now wired into TrumpRx.gov — until transparent cost-plus pricing forces pharmacy benefit managers and other middlemen out of the drug supply chain.
Declared: 2022-01-19Source ↗
He says he will not run and won't put his family through a campaign, but keeps one explicit trigger: a Trump third-term attempt, which he calls 'a true threat.'
Declared: 2025-08-15Source ↗
Does each new statement or decision square with the record? Verdicts are not accusations: both sides of the record are presented so readers can judge for themselves.
Earlier statement / action
But I think he was a lousy president before, I think he'll be a worse president this time.
Said of Trump on 'Cavuto: Coast to Coast' while campaigning as one of Kamala Harris's most visible 2024 surrogates.
Later statement / action
This is a special announcement, this is a special partnership — 559 of those drugs are ours, so we're really excited to be part of this.
Speaking beside President Trump at a White House event announcing that TrumpRx.gov would list 600+ generic drugs through partnerships with Cost Plus Drugs, Amazon Pharmacy and GoodRx.
The sight of Harris's 2024 surrogate promoting a Trump-branded platform at the White House set off days of outrage from his liberal backers and wall-to-wall cable and social coverage.
Eighteen months after calling Trump 'a lousy president' who would be 'worse this time' while campaigning to defeat him, Cuban stood beside him in the White House to celebrate plugging Cost Plus Drugs into TrumpRx. His framing: this is exactly his 'policy over politics' creed — anything that cuts Americans' drug costs is worth doing with any administration. Critics counter that he lent his credibility to a platform literally branded with Trump's name, handing an affordability win to a man he had described as a threat — evidence, they say, that business interest beat stated conviction.
Articles readers attached to their poll votes as evidence. Only pages cited independently by two or more voters are listed.
Cited by 7 voters
Cited by 5 voters
Cited by 5 voters
The statements and actions that set social media on fire — top 3, in chronological order. Every entry links to its source.
It's Elon's little echo chamber that rewards people that he rewards, and so I knew that I was going into the lion's den.
Podcast remarks after a weeks-long X feud in which Cuban defended corporate DEI programs and Musk called him 'racist' and proposed a cage match.
The Musk-Cuban-Ackman DEI brawl consumed X for weeks in January 2024; Musk branded Cuban a 'racist' and challenged him to a cage fight — Cuban's reply to Forbes: 'Lol no.'
This is a special announcement, this is a special partnership — 559 of those drugs are ours, so we're really excited to be part of this.
Speaking beside President Trump at a White House event announcing that TrumpRx.gov would list 600+ generic drugs through partnerships with Cost Plus Drugs, Amazon Pharmacy and GoodRx.
The sight of Harris's 2024 surrogate promoting a Trump-branded platform at the White House set off days of outrage from his liberal backers and wall-to-wall cable and social coverage.
In a since-deleted X post firing back at critics of the appearance ('Tell me one person who thinks that healthcare economics are well run in this country'), wrote that anyone who 'thinks I'm going to put politics ahead of helping Americans reduce their cost of healthcare and pharmaceuticals' is a 'f***ing idiot' — then posted: 'Deleted the last post because I decided cursing didn't make my point.'
Posted hours after the TrumpRx White House event as former liberal supporters accused him of selling out.
Screenshotted across X within minutes of deletion; the walk-back became its own news cycle and cemented the 'Cuban goes MAGA?' discourse.
This is a special announcement, this is a special partnership — 559 of those drugs are ours, so we're really excited to be part of this.
Speaking beside President Trump at a White House event announcing that TrumpRx.gov would list 600+ generic drugs through partnerships with Cost Plus Drugs, Amazon Pharmacy and GoodRx.
The sight of Harris's 2024 surrogate promoting a Trump-branded platform at the White House set off days of outrage from his liberal backers and wall-to-wall cable and social coverage.
In a since-deleted X post firing back at critics of the appearance ('Tell me one person who thinks that healthcare economics are well run in this country'), wrote that anyone who 'thinks I'm going to put politics ahead of helping Americans reduce their cost of healthcare and pharmaceuticals' is a 'f***ing idiot' — then posted: 'Deleted the last post because I decided cursing didn't make my point.'
Posted hours after the TrumpRx White House event as former liberal supporters accused him of selling out.
Screenshotted across X within minutes of deletion; the walk-back became its own news cycle and cemented the 'Cuban goes MAGA?' discourse.
He publicly fought Musk (and Ackman) over DEI in 2024, calling X 'Elon's little echo chamber,' while lecturing Democrats in 2025 that 'Trump sucks' is not a message. He positions himself as the tech-money centrist neither tribe controls.
It's Elon's little echo chamber that rewards people that he rewards, and so I knew that I was going into the lion's den.
Podcast remarks after a weeks-long X feud in which Cuban defended corporate DEI programs and Musk called him 'racist' and proposed a cage match.
The Musk-Cuban-Ackman DEI brawl consumed X for weeks in January 2024; Musk branded Cuban a 'racist' and challenged him to a cage fight — Cuban's reply to Forbes: 'Lol no.'
It's just 'Trump sucks.' That's the underlying thought of everything the Democrats do. 'Trump sucks.' Trump says the sky is blue. 'Trump sucks.' ... That's not the way to win! It's just not! Because it's not about Trump — it's about the people of the United States of America — and what's good for them!
On the Pod Save America podcast, telling Democrats their anti-Trump messaging is a losing strategy; date is that of the article reporting the appearance.
He called Trump a 'lousy president' as a 2024 Harris surrogate and now rules out 2028 entirely — except if Trump attempts a constitutionally barred third term, which he describes as 'changing everything.'
But I think he was a lousy president before, I think he'll be a worse president this time.
Said of Trump on 'Cavuto: Coast to Coast' while campaigning as one of Kamala Harris's most visible 2024 surrogates.
I'm not going to do it. I've said the only way I would do it is if Trump tried to run for a third term. Because then that's just changing everything, right? And that's a true threat.
On Ben Smith's Semafor podcast, ruling out a 2028 presidential run except in the event of a Trump third-term attempt; he dismissed the traditional Democratic 2028 field as 'meh.'
Earlier statement / action
But I think he was a lousy president before, I think he'll be a worse president this time.
Said of Trump on 'Cavuto: Coast to Coast' while campaigning as one of Kamala Harris's most visible 2024 surrogates.
Later statement / action
It's just 'Trump sucks.' That's the underlying thought of everything the Democrats do. 'Trump sucks.' Trump says the sky is blue. 'Trump sucks.' ... That's not the way to win! It's just not! Because it's not about Trump — it's about the people of the United States of America — and what's good for them!
On the Pod Save America podcast, telling Democrats their anti-Trump messaging is a losing strategy; date is that of the article reporting the appearance.
In 2024 Cuban's own surrogacy leaned on personal anti-Trump shots — 'lousy president... worse this time.' By mid-2025 he was scolding Democrats that 'Trump sucks' messaging is 'not the way to win.' He would say he always paired attacks with policy substance and simply drew the honest lesson from Harris's defeat; critics note he is disowning the very playbook he ran, part of a broader drift toward the administration he once attacked.
Earlier statement / action
It's just 'Trump sucks.' That's the underlying thought of everything the Democrats do. 'Trump sucks.' Trump says the sky is blue. 'Trump sucks.' ... That's not the way to win! It's just not! Because it's not about Trump — it's about the people of the United States of America — and what's good for them!
On the Pod Save America podcast, telling Democrats their anti-Trump messaging is a losing strategy; date is that of the article reporting the appearance.
Later statement / action
In a since-deleted X post firing back at critics of the appearance ('Tell me one person who thinks that healthcare economics are well run in this country'), wrote that anyone who 'thinks I'm going to put politics ahead of helping Americans reduce their cost of healthcare and pharmaceuticals' is a 'f***ing idiot' — then posted: 'Deleted the last post because I decided cursing didn't make my point.'
Posted hours after the TrumpRx White House event as former liberal supporters accused him of selling out.
Screenshotted across X within minutes of deletion; the walk-back became its own news cycle and cemented the 'Cuban goes MAGA?' discourse.
Having told Democrats in 2025 that politics should be about 'the people of the United States' rather than Trump, Cuban applied his own rule in 2026: he worked with Trump on drug prices and blasted critics who put 'politics ahead of helping Americans.' On his terms, that is coherence, not conversion. Skeptics reply that 'policy over politics' conveniently arrived just as the partnership put his own company at the center of a government platform — principle and profit pointing the same way.
Cited by 3 voters
In a since-deleted X post firing back at critics of the appearance ('Tell me one person who thinks that healthcare economics are well run in this country'), wrote that anyone who 'thinks I'm going to put politics ahead of helping Americans reduce their cost of healthcare and pharmaceuticals' is a 'f***ing idiot' — then posted: 'Deleted the last post because I decided cursing didn't make my point.'
Posted hours after the TrumpRx White House event as former liberal supporters accused him of selling out.
Screenshotted across X within minutes of deletion; the walk-back became its own news cycle and cemented the 'Cuban goes MAGA?' discourse.
I'm not going to do it. I've said the only way I would do it is if Trump tried to run for a third term. Because then that's just changing everything, right? And that's a true threat.
On Ben Smith's Semafor podcast, ruling out a 2028 presidential run except in the event of a Trump third-term attempt; he dismissed the traditional Democratic 2028 field as 'meh.'
It's just 'Trump sucks.' That's the underlying thought of everything the Democrats do. 'Trump sucks.' Trump says the sky is blue. 'Trump sucks.' ... That's not the way to win! It's just not! Because it's not about Trump — it's about the people of the United States of America — and what's good for them!
On the Pod Save America podcast, telling Democrats their anti-Trump messaging is a losing strategy; date is that of the article reporting the appearance.
But I think he was a lousy president before, I think he'll be a worse president this time.
Said of Trump on 'Cavuto: Coast to Coast' while campaigning as one of Kamala Harris's most visible 2024 surrogates.
It's Elon's little echo chamber that rewards people that he rewards, and so I knew that I was going into the lion's den.
Podcast remarks after a weeks-long X feud in which Cuban defended corporate DEI programs and Musk called him 'racist' and proposed a cage match.
The Musk-Cuban-Ackman DEI brawl consumed X for weeks in January 2024; Musk branded Cuban a 'racist' and challenged him to a cage fight — Cuban's reply to Forbes: 'Lol no.'
Launched the Mark Cuban Cost Plus Drug Company online pharmacy, selling roughly 100 generic medications at manufacturer cost plus a flat 15% markup and pledging 'radically transparent' pricing — e.g. the cancer generic imatinib at $47.40 versus a retail price above $9,657.
Launch of his flagship post-Mavericks venture, built around the mission that every American should have access to safe, affordable medicines at the lowest possible price.